How does Platelet Rich Plasma (PRP) treatment treat Osteoarthritis?
Updated: Nov 26, 2018
How does platelet rich plasma (PRP) treatment treat osteoarthritis? In short – by reducing inflammation. But how?
Knee osteoarthritis is a progressive degenerative joint disease that can be caused by aging, excessive weight, traumatic injury, strain, congenital or joint deformity. In recent years, clinicians have explored a cutting-edge treatment known as platelet-rich plasma (PRP) therapy in treating osteoarthritis with ongoing sucess with continuation of popular growth.
PRP is a very simple process whereby a small sample of blood is taken, platelets are extracted from this and then further concentrated for application. Once isolated, PRP is injected into the joint, and used clinically to promote healing properties and cellular cascade within the joint space.
Many high-quality randomised studies now has been performed on the effects of PRP versus placebo in treating knee osteoarthritis. Reports have indentified reductions in various plasma inflammatory factors and pro-angiogenic factors in patients treated with PRP compared to placebo groups. The study below concluded that the obtained clinical data illustrated reduced humoral and cellular immune responses which led to beneficial effects on histological parameters for joint osteoarthritis. In addition, The study stated that PRP treatment for knee osteoarthritis provided many beneficial effects that include reducing joint inflammation, improving cartilage destruction, reducing bone damage, and repairing joint tissue. Therefore, the study results suggest that PRP has a therapeutic effect on knee osteoarthritis and highlighted its capacity as an anti-inflammatory treatment for knee osteoarthritis. Highlighting increased clinical and therapeutic results, specifically for PRP improving symptoms with OA. More research into this area is underway to gain a larger understanding of the potential therapeutic mechanisms of Platelet Rich Plasma. https://www.ncbi.nlm.nih.gov/m/pubmed/29599843/
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